For the purpose of prevention, early diagnosis, improvement in treatment result and prediction in prognosis of oral cancer, clinico-statistical study was performed about clinical and histopathologic findings, treatment and survival rate of 150
cases of
oral squamous cell carcinoma to have been diagnosed and treated in the Department of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University from the 1st of January, 1983 to the 31th of September, 1990.
@ES The results were as follows:
@EN 1. Oral squamous cell carcinoma occured more often in males than females with a ratio 3:1, and 64.0% occured between 50 to 69 years of age with a median 56.8 years.
2. In the site distribution, 41 cases (27.3%) of the mandibular alveolus and gingiva was the most frequently involved site, followed by the maxillary alveolus and gingiva with 34 cases (22.7%), the floor of mouth with 20 cases (13.3%), the buccal
mucosa
with 12 cases, the retromolar trigone with 8 cases, the maxillary sinus and the hard palate with each 4 cases, and the soft palate and lower lip with each 1 case.
3. In the TNM classification, T4 was prominent with 85 cases (56.7%), and NO was 68 cases (45.3%). In the clinical stage grouping, stage Ⅳ was prominent with 92 cases (61.3%).
4. In the treatment of primary lesion, the treatment consisted mainly of surgical therapy was prominent with 81 cases (54.0%), 32 cases (21.3%) of which were treated by radiation therapy or chemotherapy concurrently, 11 cases (7.3%) was treated
by
rediation therapy alone and 37 cases (24.7%) did not received any therapy.
5. Using Kaplan and Meier's product-limit method, overall 3 and 5-year survival rates without regarding to the stage were 36.5% and 29.0%.
6. 5-year survival rate according to the stage grouping was 71.4% for stage Ⅰ, 61.4% for stage Ⅱ, 43.5% for stage Ⅲ, 11.1% for stage Ⅳ.
7. 5-year survival survival rate according to the treatment was 44.7% for surgically treated cases, 18.4% for the cases of radiation therapy or chemotherapy. 6 and 12 months survival rates of patients who didn't received any therapy were 45.9%
and
8.1%.
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